Virtual Microscopy Research and Benefits

Scanning system allows exact duplication of slides for use in research, publishing and education

The Virtual Microscopy Core Facility is available to students, educators, researchers, scientists and physicians who need to reproduce tissue samples in classes, presentations and publications that require high-quality images.

Diagnostic and Teaching Use

Omar Sangueza, MD, professor of pathology

The trend toward virtual pathology is obvious, and this is a critical facility. As a secondary diagnostic tool, the virtual microscopes and imaging capability are invaluable. Rather than slides piling up and having a back log of consultations, images can be taken of the slides and transferred to a secure drive daily, and can be studied anywhere in the world on a computer. This allows you to be in constant contact with residents, fellows or colleagues. In addition, you can create an enormous teaching archive to pull images quickly, searching by diagnosis directly from your computer for presentations, teaching and publications.

Research

Janel Suburu, PhD, Department of Cancer Biology

The Virtual Microscopy Core can significantly improve both the speed and quality of your research. For example, Suburu frequently used the VMC to scan slides of stained tissue sections from mice. With the virtual images, she readily quantified and presented her work with superb resolution quality. Previously, she had only the frames taken from a camera mounted on the microscope. Now, the virtual slides allow effortless perusing of every square micrometer of tissue sections from the computer screen, producing publication-quality images with just the click of a button. The virtual slides also make data sharing with colleagues simple and frustration-free.

Snezana Petrović, MD, PhD, assistant professor, Department of Physiology and Pharmacology

The Virtual Microscopy Core enormously expedites image acquisition. It also is of great assistance in simplifying presentations and publishing the results and data analysis by introducing tools available in the Olyvia software through the system. This software allows measurements and quantitative analysis in a manner not typically available to many laboratories.

Publishing Capabilities

Giuseppe Orlando, MD, PhD, transplant surgeon scientist, Wake Forest School of Medicine

Virtual microscopy allows images that are difficult to obtain with an ordinary microscopy. It creates micrographs with proper clarity, color and pixel size required by journals and other publishers when ordinary microscopes cannot do the job. For example, images of scaffolds used in research work to bioengineer kidney organoids for transplant purposes are problematic because the collagen found in a scaffold is highly refractive. That results in images that appear out of focus when taken with an ordinary microscope. The Olympus VS110® Scanner in the Virtual Microscopy lab captured well-resolved images of the scaffolding, which helped tremendously with publishing efforts.

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