About the Virtual Microscopy Scanners

Creating digital virtual images using the virtual microscopy scanners guarantees that original glass slides won’t be lost or broken. Using the two virtual microscopy scanners available in the Virtual Microscopy Core Facility also ensures that colors will not fade.

Hamamatsu NDP Nanozoomer

The NDP Scanner offers TDI line scanning perfect for archiving, teaching and presentations. It is excellent for large-scale experiments or clinical trials with many subjects.


Speed: The NDP is capable of scanning 210 slides in 15 hours through its rack system, an ideal way for students, teachers or anyone with a large-scale project.

Magnification: The NDP is available to zoom at 20X and 40X magnification, as well as z-stacks.

Presentations: The NDP allows both viewing and annotations, such as arrows, circles, text and measurements, which eliminates the need to convert the presentation into PowerPoint, which can take hours.

Olympus VS110® Scanner

The VS110 is often the scanner of choice for producing publication-quality images, which is critical for journals, where papers may be rejected because of poor color, focus or not enough DPI.


Magnification: The VS110 can magnify slides at 2X, 10X, 20X, 40X, 60X and 100X. It also is equipped with a Semrock fluorescent filter cube and a polarizer. It also can visualize and scan quantum dots.

Specialized images: The VS110 allows researchers the overview image to create a static image of an entire tissue section. It does z-stacks and EFI (which takes an image on five different levels and then compresses those into one image). EFI is important for FNAs, which have cells on multiple levels, or hard-to-focus refractive images. The VS110 also is equipped with a TMA module that scans an entire slide and creates a VI of each individual core. TMAs are particularly important in long-term studies that follow several patients over time.

Fluorescence: Fluorescent channels are scanned simultaneously with the VS110, reducing the possibility of photo bleaching. Brightfield images and fluorescent images can be overlaid in less than two minutes.

Software and Transfer

Software to view virtual images is offered free of charge, and both the NDP and VS110 scanners allow for presentations, with annotations. There is an hourly usage fee for the VS110 for annotations, as well as the creation of 3-D images.

Because the scanned images result in large-size files, the Virtual Microscopy Core Facility provides several methods of transfer to accommodate the individual user’s needs:

  • A secure, shared network drive is available to internal clients. Also available are USB external drives and CD/DVD media.
  • The Virtual Microscopy Core Facility offers options for an FTP secure server, USB external drives and CD/DVD media to external clients.
  • Slides and images sent out by the Virtual Microscopy Core Facility are done through secure mail delivery services at the expense of the client.

Call +1.336.716.1568 or email vmcore@wakehealth.edu.

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